[PDF.47vr] Statistical Monitoring of Clinical Trials: A Unified Approach (Statistics for Biology and Health)

Statistical Monitoring of Clinical Trials: A Unified Approach (Statistics for Biology and Health)

[PDF.uu32] Statistical Monitoring of Clinical Trials: A Unified Approach (Statistics for Biology and Health)

Statistical Monitoring of Clinical  Michael A. Proschan, K. K. Gordon Lan, Janet Turk Wittes epub
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 | #661185 in Books |  Michael Proschan |  2007-11-26 | Original language:English | PDF # 1 |  9.21 x.69 x6.14l,1.14 | File type: PDF | 268 pages

 | Statistical Monitoring of Clinical Trials A Unified Approach

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||0 of 0 people found the following review helpful.| Provides good mathematical background on monitoring clinical trials|By W. YIP|It is a more advance mathematical treatment on group sequential methods. Besides the basic, the book covers some topics that are still in development (e.g. What is the p-value when the trial is stopped early ?) while some are not covered (e.g. repeated confidence interval). I find the book difficult

The approach taken in this book is, to studies monitored over time, what the Central Limit Theorem is to studies with only one analysis. Just as the Central Limit Theorem shows that test statistics involving very different types of clinical trial outcomes are asymptotically normal, this book shows that the joint distribution of the test statistics at different analysis times is asymptotically multivariate normal with the correlation structure of Brownian motion ("the ...

You can specify the type of files you want, for your device.Statistical Monitoring of Clinical Trials: A Unified Approach (Statistics for Biology and Health)   |  Michael A. Proschan, K. K. Gordon Lan, Janet Turk Wittes. I really enjoyed this book and have already told so many people about it!

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