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Sample Size Determination in Clinical Trials with Multiple Endpoints (SpringerBriefs in Statistics)

Takashi Sozu, Tomoyuki Sugimoto, Toshimitsu Hamasaki, Scott R. Evans




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 | #3574759 in Books |  2015-08-22 |  2015-09-04 | Original language:English | PDF # 1 |  9.25 x.24 x6.10l,.35 | File type: PDF | 95 pages

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This book integrates recent methodological developments for calculating the sample size and power in trials with more than one endpoint considered as multiple primary or co-primary, offering an important reference work for statisticians working in this area.

The determination of sample size and the evaluation of power are fundamental and critical elements in the design of clinical trials. If the sample size is too small, important effects may go unnoticed; if th...

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