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Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine

Fabrice Lejeune, Hana Benhabiles, Jieshuang Jia




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 | #1582016 in Books |  Fabrice Lejeune Jieshuang Jia Hana Benhabiles |  2016-03-28 |  2016-03-14 | Original language:English | PDF # 1 |  9.00 x.45 x6.00l,.0 | File type: PDF | 190 pages

 | Nonsense Mutation Correction in Human Diseases An Approach for Targeted Medicine

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Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD).

It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinica...

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