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JAK-STAT Pathway in Disease

Richard H. Bell Jr.




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 | #2475327 in Books |  2005-11-10 | Original language:English | PDF # 1 | File type: PDF | 341 pages

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This book reviews current understanding of the biological roles of the signal transducer and activator of transcription (STAT) proteins and their dysregulation in diseases. STAT proteins were named after their role as signal transducers and activators of transcription. STAT proteins are highly conserved among species, thus reflecting the importance of these transcription factors in controlling processes such as development, cell growth and homeostasis. STAT1 and STAT2 we...

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