[PDF.22gk] Group Sequential and Confirmatory Adaptive Designs in Clinical Trials (Springer Series in Pharmaceutical Statistics)

Group Sequential and Confirmatory Adaptive Designs in Clinical Trials (Springer Series in Pharmaceutical Statistics)

[PDF.mi02] Group Sequential and Confirmatory Adaptive Designs in Clinical Trials (Springer Series in Pharmaceutical Statistics)

Group Sequential and Confirmatory  Gernot Wassmer, Werner Brannath epub
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 | #2184500 in Books |  2016-07-05 | Original language:English | PDF # 1 |  9.21 x.75 x6.14l,.0 | File type: PDF | 301 pages

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This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven change of relevant aspects of the study design at interim stages. Thi...

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