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Dose Finding by the Continual Reassessment Method (Chapman & Hall/CRC Biostatistics Series)

Ying Kuen Cheung




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 | #3067377 in Books |  Chapman n Hall/CRC |  2011-03-29 | Original language:English | PDF # 1 |  9.30 x.60 x6.20l,.95 | File type: PDF | 200 pages

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As clinicians begin to realize the important role of dose-finding in the drug development process, there is an increasing openness to "novel" methods proposed in the past two decades. In particular, the Continual Reassessment Method (CRM) and its variations have drawn much attention in the medical community, though it has yet to become a commonplace tool. To overcome the status quo in phase I clinical trials, statisticians must be able to design trials using the CRM i...

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