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DNA Polymerases: Discovery, Characterization and Functions in Cellular DNA Transactions

Ulrich Hubscher, Silvio Spadari, Giuseppe Villani, Giovanni Maga




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 | #4759561 in Books |  2010-04-14 | Original language:English | PDF # 1 |  9.80 x.80 x6.50l,1.70 | File type: PDF | 340 pages

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Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, genome sequencing, nucleic acids-based diagnostics and in techniques to analyze ancient and otherwise damaged DNA. Moreover, some...

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