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DNA Methylation and Cancer (Current Topics in Microbiology and Immunology)

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[PDF.bn67] DNA Methylation and Cancer (Current Topics in Microbiology and Immunology)

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 | #6710796 in Books |  2000-03-30 | Original language:English | PDF # 1 |  9.25 x6.25 x.50l,.0 | File type: PDF | 170 pages

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This book is a comprehensive survey of new and exciting developments regarding the role of DNA methylation in human cancer. Issues related to the mutagenicity of 5-methylcytosine and the increase in the interaction of chemical and physical carcinogens with these residues is discussed. The book summarizes the modulation of viral gene expression and the silencing of tumor suppressor genes and illustrates mechanisms by which the methylation signal is translated into altered...

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