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Cilia and Nervous System Development and Function

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 | #7592558 in Books |  Springer |  2013-01-19 | Original language:English | PDF # 1 |  9.20 x.90 x6.20l,1.55 | File type: PDF | 278 pages

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Cilia are tiny microtubule-based organelles projecting from the plasma membrane of practically all cells in the body. In the past 10 years a flurry of research has indicated a crucial role of this long-neglected organelle in the development and function of the central nervous system. A common theme of these studies is the critical dependency of signal transduction of the Sonic hedgehog, and more recently, Wnt signaling pathways upon cilia to regulate fate decisions and m...

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