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Bayesian Designs for Phase I–II Clinical Trials (Chapman & Hall/CRC Biostatistics Series)

Ying Yuan, Hoang Q. Nguyen, Peter F. Thall




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 | #1784875 in Books |  2016-06-22 | Original language:English | PDF # 1 |  9.25 x6.25 x.75l,.0 | File type: PDF | 324 pages

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Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources.

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