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ABC Transporters - 40 Years on

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 | #5720734 in Books |  Ingramcontent |  2015-12-16 | Original language:English | PDF # 1 |  9.21 x.88 x6.14l,.0 | File type: PDF | 376 pages

 | ABC Transporters 40 Years on 2016

|

This book provides new structural, biochemical, and clinical information on ABC transporters.  The authors explore and describe the state of the art of research, knowledge, and prospects for the future for this important family of proteins. The first ABC transporter was discovered in 1973 and was named P-glycoprotein. It elicits resistance to cytotoxic drugs, chiefly in human tumours, within which chemotherapy failure is observed in about 50% of cases. Together w...

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